OneLife enzymatics : protecting against biofilm contamination where standard detergents and disinfectants fail.
99% OF BACTERIA HIDE IN BIOFILMS.
O’Toole, G., Kaplan, H. B. Kolter, R. Biofilm Formation as Microbial Development. Annu. Rev. Microbiol. 54, 49‑79 (2000)
Why are biofilms an issue?
Biofilms are responsible for 65% of all infections.¹
are subjected to contamination by biofilms.
Cleaning is crucial
It is impossible to disinfect or even sterilize inadequately-cleaned medical devices.4
Bacteria are up to 1000x more tolerant to biocides if in a biofilm. ⁷
is favored inside biofilms due to horizontal transfer of genes carrying antibiotics-resistance.
BIOFILMS IN BRIEF
Most biofilms are multi-species. Even non biofilm-forming microbes can be sheltered in a biofilm. (incl. multi-drug resistant bacteria like MRSA, CRE, Staphylococcus aureus, Pseudomonas aeruginosa or Legionella, Escherichia coli, Viruses and Fungi) ⁶
Biofilms develop frequently on Medical Devices.
Horizontal transfer of genes carrying antiobiotics-resistance is favored inside biofilms. ⁸
Biofilms form a protective barrier around infectious micro-organisms. Biofilms enhance survival of exposure to antimicrobials.
Inorganic and organic materials interfere with the effectiveness / antimicrobial activity of disinfectants and sterilization.³
Disinfectants are mostly tested against planktonic (free) bacteria, although 99% of bacteria naturally exist in a biofilm.
More detailed facts in : Biofilm knowledge center >
OneLife's 2 step
approach to achieve