Enzymes for patients’ safety
99% OF BACTERIA HIDE IN BIOFILMS.
O’Toole, G., Kaplan, H. B. Kolter, R. Biofilm Formation as Microbial Development. Annu. Rev. Microbiol. 54, 49‑79 (2000)
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a recognition that WE consistently meet customer and regulatory requirements.
OneLife strengthens its fight against Hospital Acquired infections.
enziQure® shows significant biofilm dispersion VS. CURRENT SOLUTIONS
UCL study (POSTER - SF2H)
CORRELATION BIOFILM BIOMASS & BACTERIAL ELIMINATION : in vitro model for endosopy.
CHU LIEGE STUDY
Comparison in situ of enzymatic VS. noN-enzymatiC solutions
Why are biofilms an issue?
Biofilms are responsible for 65% of all infections.¹
are subjected to contamination by biofilms.
Cleaning is crucial
It is impossible to disinfect or even sterilize inadequately-cleaned medical devices.4
Bacteria are up to 1000x more tolerant to biocides if in a biofilm. ⁷
is favored inside biofilms due to horizontal transfer of genes carrying antibiotics-resistance. ⁵
BIOFILMS IN BRIEF
Most biofilms are multi-species. Even non biofilm-forming microbes can be sheltered in a biofilm (incl. multi-drug resistant bacteria like MRSA, CRE, Staphylococcus aureus, Pseudomonas aeruginosa or Legionella, E. coli, Viruses and Fungi). ⁶
Biofilms develop frequently on Medical Devices.
Horizontal transfer of genes carrying antiobiotics-resistance is favored inside biofilms. ⁸
Biofilms form a protective barrier around infectious micro-organisms and enhance survival of exposure to antimicrobials.
Inorganic and organic materials interfere with the effectiveness of disinfectants and sterilization.³
Disinfectants are mostly tested against planktonic (free) bacteria, although 99% of bacteria naturally exist in a biofilm.
More detailed facts in : Biofilm knowledge center >
OneLife's 2 step
approach to achieve